Fig. 4

YTHDF2 can activate NF-κB through suppressing UBXN1 expression. A UBXN1 mRNA expression in cells with or without YTHDF2 siRNA. *P < 0.05; **P < 0.01; ****P < 0.0001. B YTHDF2, p65, pp65, and UBXN1 protein expression in cells with or without YTHDF2 siRNA. C–E The quantified data of protein expression levels in cells with or without YTHDF2 siRNA. *P < 0.05; **P < 0.01; ***P < 0.001. F UBXN1 mRNA expression in cells with or without YTHDF2 overexpression (OE). **P < 0.01; ***P < 0.001. G YTHDF2, p65, pp65, and UBXN1 protein expression in cells with or without YTHDF2 OE