Fig. 7

LIC frequencies of AML-491 after NK cell-mediated lysis with the 2 × SIRPα-αCD123 fusion antibody. A Engraftment at each injected cell dose for each antibody. Residual AML cells were counted during cell sorting before injection. B LIC frequencies were estimated using extreme limiting dilution analysis software [35]. Horizontal lines indicate the estimated LIC frequencies, and the bars indicate 95% confidence intervals