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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: Dysregulated tumor-associated macrophages in carcinogenesis, progression and targeted therapy of gynecological and breast cancers

Fig. 4

Characteristics of TAMs among gynecological and breast cancers. a ER+ breast cancer patients had lower survival rates. TAMs up-regulated HOXB13 and down-regulated IL-6 and ER expression. b The cascade of estrogen, CXCL8 and IL-6 regulated ovarian cancer cell growth. c TAMs promoted EMT in endometrial carcinoma through HOXB13. d The type of HPV infection was associated with the number of TAMs and IL-10 expression. TAMs up-regulated the expression of IL-6, MMP-9 and GDF15 in cervical cancer

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