Fig. 5From: Targeting the histone H3 lysine 79 methyltransferase DOT1L in MLL-rearranged leukemiasOverview of disrupting PPIs that involve the epigenetic regulation of DOT1L. Disruptions of PPIs include DOT1L interaction with fusion partners, ubiquitin, histone cross talk, the acidic patch, and other interactors, such as Bat3 and lncRNA LAMP5-AS1Back to article page