Fig. 2
From: The potential role of N7-methylguanosine (m7G) in cancer
The cross talk between m7G modification and other posttranscriptional modifications. The m6Am methyltransferase PCIF1 catalyzes m6Am modification adjacent to the m7G cap, which enhances resistance to DCP2-dominated decapping. The m6Am methyltransferase METTL14 installs m6Am modification at an internal site in U2 snRNA, ultimately influencing global alternative RNA splicing