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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: Reshaping the systemic tumor immune environment (STIE) and tumor immune microenvironment (TIME) to enhance immunotherapy efficacy in solid tumors

Fig. 4

STIE and TIME in brain metastasis. The figure shows the modulating role of systemic tumor immune environment (STIE) on the spread of primary tumor to the brain metastasized sites. It is relevant to local therapy such as radiation therapy (RT) and systemic therapy like PD-1 on the left panel and the components of STIE which include all circulating immune modulating molecules such as cytokines like TGF-β1, IDO biomarkers, Artemin and circulating immune cells such as lymphocytes on the right panel

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Journal of Hematology & Oncology

ISSN: 1756-8722

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