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Table 2 Characteristics of the present cohort according to thrombosis and bleeding status

From: Thrombotic and bleeding complications in patients with chronic lymphocytic leukemia and severe COVID-19: a study of ERIC, the European Research Initiative on CLL

 

Thrombosis

Bleeding

No (n = 409)

Yes (n = 51)

No (n = 445)

Yes (n = 23)

Gender, male, n%

283/409 (69.2)

35/51 (68.6)

313/445 (70.3)

15/23 (65.2)

Age, median (25–75th percentile)

70 (63‒79)

67 (61‒77)

69 (63–78)

78 (66–86)*

Smoking

    

 Never, n%

253/378 (66.9)

31/48 (64.6)

275/414 (66.4)

13/21 (61.9)

 Ex-smoker, n%

96/378 (25.4)

13/48 (27.1)

108/414 (26.1)

6/21 (28.6)

 Current smoker, n%

29/378 (7.7)

4/48 (8.3)

31/414 (7.5)

2/21 (9.5)

Obesity, n%

71/390 (18.2)

8/50 (16.0)

73/425 (17.2)

5/21 (23.8)

Presence of any comorbidity, n%

339/408 (83.1)

45/50 (90.0)

367/443 (82.8)

19/23 (82.6)

Number of comorbidities

    

 No comorbidities, n%

69/408 (16.9)

5/50 (10.0)

76/443 (17.2)

4/23 (17.4)

 1 comorbidity, n%

86/408 (21.1)

14/50 (28.0)

91/443 (20.5)

6/23 (26.1)

 > 2 comorbidities, n%

253/408 (62.0)

31/50 (62.0)

276/443 (62.3)

13/23 (56.5)

Type of comorbidities

    

 Other respiratory, n%

25 (6.1)

6 (12.0)

33 (7.4)

2 (8.7)

 Asthma, n%

12 (2.9)

1 (2.0)

14 (3.2)

0 (0)

 COPD, n%

26 (6.4)

1 (2.0)

30 (6.8)

1 (4.3)

 Other cardiovascular, n%

31 (7.6)

8 (16.0)*

39 (8.8)

0 (0)

 Cardiac failure, n%

12 (2.9)

1 (2.0)

11 (2.5)

2 (8.7)

 Arrhythmias, n%

35 (8.6)

8 (16.0)

40 (9.0)

4 (17.4)

 Coronary artery disease, n%

43 (10.5)

4 (8.0)

47 (10.6)

1 (4.3)

 Hypertension, n%

202 (49.5)

23 (46.0)

216 (48.8)

12 (52.2)

 Diabetes, n%

95 (23.3)

11 (22.0)

101 (22.8)

4 (17.4)

 Other hematological malignancy, n%

6 (1.5)

2 (4.0)

6 (1.4)

1 (4.3)

 Other non-hematological malignancy, n%

30 (7.4)

5 (10.0)

35 (7.9)

2 (8.7)

 Chronic renal disease, n%

26 (6.4)

4 (8.0)

27 (6.1)

2 (8.7)

CIRS, median (25–75th percentile)

4 (2‒7)

4 (2‒7)

4 (2–7)

4 (2–7)

  1. COPD chronic obstructive pulmonary disease, CIRS cumulative illness rating scale
  2. *p < 0.05