Fig. 4
From: Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo
Depletion of ITGB4 causes increased apoptosis, but unaltered proliferation in vivo. Percentage of apoptotic nuclei (A), Bim+ tumor cells (B), pH2AX+ nuclei (C) and Ki-67+ nuclei (D) per viewing field (VF) in xenograft tumor tissues and corresponding representative staining microphotographs (arrowheads in (A) indicate apoptotic bodies). Bar charts represent mean + SD of given sample sizes. ***p < 0.001