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Table 2 Reported adverse events from glofitamab therapy

From: Glofitamab therapy for diffuse large B cell lymphoma: latest updates from the 2022 ASH Annual Meeting

Author

Study

Regimen

Grade ≥ 3 AEs

Grade 1–2 CRS

Grade 3–5 CRS

Max S. Topp

Phase Ib

Glofitamab combined with R-CHOP

71.4%

10.7%

0

Martin Hutchings

Phase I

RO7227166 combined with glofitamab

57.2%

54.3%

0

Anna Dodero

Retrospective

Glofitamab

–

–

–

Martin Hutchings

Retrospective

Glofitamab

–

–

–

Burhan Ferhanoglu

Retrospective

(compassionate use)

Glofitamab

23%

28.6%

8.6%

  1. CRS cytokine release syndrome, AEs adverse events