Fig. 1

Treatment-free remission according to several variables of clinical relevance. A Molecular recurrence-free survival after TKI discontinuation (N = 46). The median molecular follow-up after TKI discontinuation was 31 months (range 2–38 months) overall and 34 months (range, 27 to 38 months) for the 30 patients in molecular remission without treatment. B Duration in months of DMR before stopping TKI in relapsed vs non-relapsed patients. C Molecular recurrence-free survival according to duration of stable DMR prior to TKI discontinuation (< 40 vs. > 40 months): Log-rank [Mantel-Cox] test: p = 0.004 HR = 4.29 CI: 0.64 to 28.59. D Molecular recurrence-free survival according to prior TKI duration (< 5.8 vs. > 5.8 years): Log-rank [Mantel-Cox] test: p = 0.039 HR = 2.80 CI 0.68–11.51)