Fig. 2

Amino acid metabolism in B cells. Several amino acids are associated with B cell function and differentiation, and threonine can further affect the differentiation and function of monocytes. The solid line represents certain effects and reactions in B cells, and the dashed line represents potential effects and reactions in B cells. The arrow line represents activation and the line with a bar at the end represents inhibition. GABA γ-aminobutyric acid; GAD Glutamate decarboxylase; Glu Glutamate; His Histidine; IgG Immunoglobulin G; IgM Immunoglobulin M; IL Interleukin; Leu Leucine; mTORC1 Mechanistic target of rapamycin kinase complex 1; SLC Solute carrier; Teff cell Effector T cell