Table 1 Distribution of cancer types by study phase of clinical trials for anticancer mRNA therapeutics
From: Clinical development of mRNA therapies against solid tumors
Cancer type | Phase I | Phase II | Phase III | Total |
|---|---|---|---|---|
Melanoma | 16 | 6 | 1 | 23 |
Unspecific solid tumors | 21 | 1 | 0 | 22 |
Renal cell carcinoma | 6 | 5 | 1 | 12 |
Prostate cancer | 7 | 2 | 0 | 9 |
Non-small cell lung cancer | 6 | 3 | 0 | 9 |
Glioblastoma | 5 | 4 | 0 | 9 |
Breast cancer | 5 | 0 | 0 | 5 |
Ovarian cancer | 2 | 1 | 0 | 3 |
Hepatocellular carcinoma | 2 | 0 | 0 | 2 |
Head and neck squamous cell carcinoma | 1 | 1 | 0 | 2 |
Colorectal cancer | 1 | 1 | 0 | 2 |
Breast cancer and melanoma | 2 | 0 | 0 | 2 |
Acute myeloid leukemia | 2 | 0 | 0 | 2 |
Pancreatic cancer | 1 | 0 | 0 | 1 |
Multiple myeloma | 1 | 0 | 0 | 1 |
Gastric cancer | 0 | 1 | 0 | 1 |
Esophageal and non-small cell lung cancer | 0 | 1 | 0 | 1 |
Chronic lymphocytic leukemia | 1 | 0 | 0 | 1 |
Bladder cancer | 0 | 1 | 0 | 1 |
Total | 79 | 27 | 2 | 108 |