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Table 1 Properties of bispecific antibodies for multiple myeloma

From: Bispecific antibodies targeting BCMA, GPRC5D, and FcRH5 for multiple myeloma therapy: latest updates from ASCO 2023 Annual Meeting

Product

Target

Administration

Reference

Teclistamab

BCMA × CD3

SC

[1]

Elranatamab

BCMA × CD3

SC

[4]

Linvoseltamab

BCMA × CD3

IV

[7]

F182112

BCMA × CD3

IV

[8]

Talquetamab

GPRC5D × CD3

SC

[9]

Cevostamab

FcRH5 × CD3

IV

[13]

  1. Abbreviations: BCMA, B-cell maturation antigen; bsAbs, bispecific antibodies; FcRH5, Fc receptor-homolog 5; GPRC5D, G protein-coupled receptor family C group 5 member D; IV, intravenous; SC, subcutaneous