Fig. 8

NILK-2301 concentrations versus time in cynomolgus monkeys. Animals received a single IV administration at A 0.5 mg/kg, B 10 mg/kg, or C 20 mg/kg SC, respectively. The four differently colored curves represent the individual animals (two females [solid lines] and two males [dashed lines]). PK parameters are summarized in Additional file 1: Table S5 (IV) and S6 (SC). LLOQ, lower limit of quantification