Fig. 2

Intra-cellular MLOs within a eukaryotic cell. MLOs are distributed in the nucleus, nuclear membrane, cytoplasm, and plasma membranes of cells. Nucleolus, perinucleolar compartments, paraspeckles, Cajal bodies, transcription condensates, Gems, DNA repair foci, nuclear stress bodies, PcG bodies, histone locusbody, PML bodies, DNA replication bodies, polycombs, SPOP/DAXX bodies, super enhancers, heterochromatin, and amyloid bodies (located in nucleolus) are located in the nuclear by the LLPS. Whereas some MLOs are distributed in the nuclear membrane (Babliani bodies), cytoplasm (such as sec bodies, cGAS-DNA condensates, ER associated TIS granules, autophagosome cargo condensates, stress granule, P granules, U bodies, Virus factories, Numb/pon complex, RNA transport granules, centrosome, inclusion bodies, siganling puncta, GW bodies, germ granules, transport RNP, and proteosome bodies, metabolic granules, keratin granules), and cell plasma membrane (such as immune synapse densities, Numb/pon complex, Nephrin adhesion complexes/ signaling clusters, T cell microclusters, and ZO mediated tight junction)