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Table 2 Metabolic features of immune cells in the TME

From: Metabolic reprogramming in the tumor microenvironment of liver cancer

 Cell types

Metabolic characteristics

 

Glycolysis

OXPHOS

FAO

AA

PPP

HBP

Immune activation

Teff

 +  + 

 + 

 

 + 

 + 

 + 

Tem

 +  + 

 + 

    

NK

 + 

 + 

    

M1φ

 +  + 

   

 + 

 

DC

 +  + 

     

Immunosuppression

Treg

 

 +  + 

 + 

 + 

  

MDSC

 + 

 

 +  + 

 + 

  

M2φ

 

 + 

 +  + 

 + 

  
  1.  +  + Significantly upregulated; + Upregulated; OXPHOS oxidative phosphorylation; FAO fatty acid oxidation; AA amino acid; PPP pentose phosphate pathway; and HBP hexosamine biosynthetic pathway
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Journal of Hematology & Oncology

ISSN: 1756-8722

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