Fig. 1

A schematic of the crosstalk between major inflammatory cells and inflammatory molecules in the tumor microenvironment. The major inflammatory cells include T helper (Th1) cell, regulatory T cells (Tregs), cytotoxic CD8 + T cells, macrophages, neutrophils, myeloid-derived suppressor cells (MDSCs), natural killer (NK) cells, and dendritic cells (DCs). Figures created with BioRender. Abbreviations: CXCR, CXC-chemokine receptor; CXCL, chemokine (C-X-C motif) ligand; TGF-β, transforming growth factor-β; TNF, tumor necrosis factor; IL, interleukin; IFN, interferon