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Table 3 Progression Free Survival and 2-year OS in IPASS Study based on EGFR mutation

From: Updates in non-small cell lung cancer - insights from the 2009 45th annual meeting of the American Society of Clinical Oncology

Outcome

Gefitinib

Carboplatin+Paclitaxel

HR (95% CI)

P Value

Median PFS, months

    

EGFR mutation

9.5

6.3

0.48 (0.36-0.64)

< 0.0001

No EGFR mutation

1.5

5.5

2.85 (2.05-3.98)

< 0.0001

2-year OS, %

    

EGFR mutation

71.2

66.7

0.78 (0.50-1.20)

Not Significant

No EGFR mutation

42.9

50.6

1.38 (0.92-2.09)

Not Significant

  1. PFS, progression free survival; OS, overall survival; HR, hazard ratio; EGFR, epidermal growth factor receptor.
  2. Reference: [30]