Skip to main content
Figure 5 | Journal of Hematology & Oncology

Figure 5

From: Molecular mechanism of the schedule-dependent synergistic interaction in EGFR-mutant non-small cell lung cancer cell lines treated with paclitaxel and gefitinib

Figure 5

Sequential modulation of EGFR phosphorylation. Cells were exposed to the IC50 dose of gefitinib and paclitaxel using different sequences. *Paclitaxel significantly activated the EGFR pathway compared with control after paclitaxel exposure for 24 h (p < 0.05). # p < 0.05. The phosphorylated EGFR (p-EGFR) level after treatment with paclitaxel followed by gefitinib was lower than that for gefitinib followed by paclitaxel.

Back to article page

Journal of Hematology & Oncology

ISSN: 1756-8722

Contact us