Figure 8
Sequential modulation of TGFα release and expression. Cells were exposed to IC50 dose of paclitaxel and gefitinib with different sequence. A, standard enzyme-linked immunosorbent assay analysis of soluble TGFα levels in PC-9, Hcc827 and H1650 cells. *p < 0.05, significantly different from control. #P < 0.05, T→G VS G→T. B, reverse transcription-polymerase chain reaction analysis of TGFα expression. *p < 0.05, significantly different from control. #P < 0.05, T→G vs. G→T.