Figure 1

Structure of the RIP140 gene and protein. Schematic representations of the RIP140 gene and protein (not scaled). (Top panel) The two promoters are shown together with the four exons (E1 to E4) which are represented by small rectangles, the blue one corresponding to the RIP140 coding sequence. (Middle panel) The box represents the RIP140 molecule showing the four different repressive domains (RD). (Bottom panel) The different nuclear signaling pathways either inhibited (−) or stimulated (+) by RIP140 are indicated.