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Table 2 A summary of various miRNA delivery methods and their potential modulatory effects

From: MiRNA-based therapeutic intervention of cancer

Delivery method

Modulatory effect

Viral based

Replacement/inhibition

 Lentiviral

 Adenoviral

 Adeno-associated viral

 Viral derived exosomes

Nanoparticle based

Replacement/inhibition

 Inorganic

  Gold particles

  Carbon particles

  Silica particles

  Organic polymers

 Poly-lacticco-glycolic acid

  Polyethylenimine

  Poly-dimethylaminoethyl- methacrylate

  Lipid nanoparticles

Sponges

Inhibition