Erratum
Open Access
Erratum to: Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia
Journal of Hematology & Oncology201710:49
https://doi.org/10.1186/s13045-017-0419-x
© The Author(s). 2017
Received: 8 February 2017
Accepted: 8 February 2017
Published: 17 February 2017
The original article was published in Journal of Hematology & Oncology 2017 10:39
Erratum
The original article [1] contained an error whereby the formatting of Table 1 was not presented correctly; this error has now been corrected.
Table 1
Clinical and molecular characteristics of TCGA AML patients according to the mutation and/or copy number variation status of genes encoding m6A regulatory enzymes
Mutation and/or CNV | CNV onlya | Mutation | |||||||
|---|---|---|---|---|---|---|---|---|---|
Yes (n = 23) | No (n = 168) | P | Yes (n = 18) | No (n = 168) | P | Yes (n = 5) | No (n = 186) | P | |
Age | 0.083 | 0.193 | 0.205 | ||||||
Median (range) | 65 (18–81) | 57 (21–88) | 62.5 (18–81) | 57 (21–88) | 65 (45–76) | 57.5 (18–88) | |||
Sex, no. (%) | 0.123 | 0.321 | 0.376 | ||||||
Male | 16 (8.4) | 87 (45.5) | 12 (6.5) | 87 (46.8) | 4 (2.1) | 99 (51.8) | |||
Female | 7 (3.7) | 81 (42.4) | 6 (3.2) | 81 (43.5) | 1 (0.5) | 87 (45.5) | |||
BM blast | 0.072 | 0.038 | 0.915 | ||||||
Median % (range) | 60 (30–97) | 73 (30–100) | 54 (30–97) | 73 (30–100) | 75 (33–90) | 72 (30–100) | |||
WBC, ×103/mm3 | 0.084 | 0.047 | 0.889 | ||||||
Median (range) | 5.4 (0.7–202.7) | 17.5 (0.4–298.4) | 5.2 (2.3–101.3) | 17.45 (0.4–298.4) | 14.5 (2.3–101.3) | 15.6 (0.4–298.4) | |||
Cytogenetic risk, no. (%) | <0.0001 | <0.0001 | 0.483 | ||||||
Favorable | 0 (0) | 37 (19.4) | 0 (0) | 37 (19.9) | 0 (0) | 37 (19.4) | |||
Intermediate | 4 (2.1) | 105 (55) | 1 (0.5) | 105 (56.5) | 3 (1.6) | 106 (55.5) | |||
Unfavorable | 19 (9.9) | 21 (11) | 17 (9.1) | 21 (11.3) | 2 (1) | 38 (19.9) | |||
Missing data | 0 (0) | 5 (2.6) | 0 (0) | 5 (2.6) | 0 (0) | 5 (2.6) | |||
Mutation, no./total no. (%) | |||||||||
FLT3 | 1/23 (4.3) | 53/168 (31.5) | 0.005 | 0/18 (0) | 53/168 (31.5) | 0.002 | 1/5 (20) | 53/186 (28.4) | 1.000 |
NPM1 | 1/23 (4.3) | 51/168 (30) | 0.006 | 0/18 (0) | 51/168 (30.3) | 0.004 | 1/5 (20) | 51/186 (27.4) | 1.000 |
DNMT3A | 4/23 (17.4) | 43/168 (25.6) | 0.453 | 2/18 (11.1) | 43/168 (25.6) | 0.249 | 2/5 (40) | 45/186 (24.2) | 0.598 |
IDH1 or IDH2 | 1/23 (4.3) | 34/168 (20.2) | 0.084 | 0/18 (0) | 34/168 (20.2) | 0.048 | 1/5 (20) | 34/186 (18.3) | 1.000 |
NRAS or KRAS | 3/23 (13) | 20/168 (11.9) | 0.744 | 3/18 (16.7) | 20/168 (11.9) | 0.471 | 0/5 (0) | 23/186 (12.4) | 1.000 |
RUNX1 | 2/23 (8.7) | 17/168 (10.1) | 1.000 | 0/18 (0) | 17/168 (10.1) | 0.380 | 2/5 (40) | 17/186 (9.1) | 0.078 |
TET2 | 1/23 (4.3) | 15/168 (8.9) | 0.698 | 1/18(5.6) | 15/168 (8.9) | 1.000 | 0/5 (0) | 16/186 (8.6) | 1.000 |
TP53 | 15/23 (65.2) | 1/168 (0.6) | <0.0001 | 13/18 (72.2) | 1/168 (0.6) | <0.0001 | 2/5 (40) | 14/186 (7.5) | 0.057 |
CEBPA | 2/23 (8.7) | 10/168 (6.0) | 0.641 | 2/18 (11.1) | 10/168 (6.0) | 0.327 | 0/5 (0) | 12/186 (6.5) | 1.000 |
WT1 | 0/23 (0) | 12/168 (7.1) | 0.366 | 0/18 (0) | 12/168 (7.1) | 0.610 | 0/5 (0) | 12/186 (6.5) | 1.000 |
PTPN11 | 2/23 (8.7) | 6/168 (3.6) | 0.248 | 2/18 (11.1) | 6/168 (3.6) | 0.175 | 0/5 (0) | 8/186 (4.3) | 1.000 |
KIT | 1/23 (4.3) | 6/168 (3.6) | 0.599 | 0/18 (20) | 6/168 (3.6) | 1.000 | 1/5 (20) | 6/186 (3.2) | 0.172 |
Furthermore, the error was mistakenly carried forward by the production team handling this article, and thus was not the fault of the authors.
Notes
Declarations
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Authors’ Affiliations
(1)
Gene & Stem Cell Therapy Program, Centenary Institute, University of Sydney
(2)
Gene Regulation in Cancer Laboratory, Centenary Institute, University of Sydney
(3)
Sydney Medical School, University of Sydney
(4)
Cell and Molecular Therapies, Royal Prince Alfred Hospital
References
- Kwok, et al. Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia. J Hematol Oncol. 2017;10:39.View ArticlePubMedPubMed CentralGoogle Scholar
Copyright
© The Author(s). 2017
