Journal of Hematology & Oncology is the official journal of the Chinese American Hematologist and Oncologist Network.
JAG1 overexpression contributes to Notch1 signaling and the migration of HTLV-1-transformed ATL cells
HTLV-1 is a retrovirus that infects over 20 million people worldwide and is responsible for the hematopoietic malignancy adult T cell leukemia (ATL). We previously demonstrated that Notch is constitutively act...