Journal of Hematology & Oncology is the official journal of the Chinese American Hematologist and Oncologist Network.
B-Raf and the inhibitors: from bench to bedside
The B-Raf protein is a key signaling molecule in the mitogen activated protein kinase (MAPK) signaling pathway and has been implicated in the pathogenesis of a variety of cancers. An important V600E mutation h...