Journal of Hematology & Oncology is the official journal of the Chinese American Hematologist and Oncologist Network.
Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy
The mammalian target of rapamycin (mTOR) is an intracellular serine/threonine protein kinase positioned at a central point in a variety of cellular signaling cascades. The established involvement of mTOR activ...