Journal of Hematology & Oncology is the official journal of the Chinese American Hematologist and Oncologist Network.
Targeting the IDO1 pathway in cancer: from bench to bedside
Indoleamine 2, 3-dioxygenases (IDO1 and IDO2) and tryptophan 2, 3-dioxygenase (TDO) are tryptophan catabolic enzymes that catalyze the conversion of tryptophan into kynurenine. The depletion of tryptophan and ...